It can be used in descriptive anatomy - He's a fucking asshole.

It can be used to tell time - It's five fucking thirty.

It can be used in business - How did I get this fucking job?

It can be a prediction - Oh, will I get fucked.

It can have maternal connotations - as in "Mother Fucker."

It can be nautical - Fuck the Admiral.

It can be political - Fuck Obama.

It can open the door to wonderful relationships - "let's fuck."

It can be used to enhance the meaning of a word - as in infuckingcredible or absofuckinglutely.

The mind is fairly boggled at the many, many creative uses. How could anyone be offended when you say "fuck?"